Preclinical study
Selank and colon morphology during restraint stress
Male rats underwent repeated restraint while investigators examined colon-wall morphology and corticosterone-related changes.
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Preclinical study
Reading a MOTS-c metabolomics study
Blood metabolite patterns offer clues about mechanisms in a diet-induced obesity model.
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Selank after prolonged ethanol exposure in rats
Rats with prolonged ethanol exposure underwent object-recognition testing and regional brain neurotrophin measurements during withdrawal.
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Selank and the microbiota of stressed rats
A restraint-stress rat experiment assessed intestinal microbial populations with and without peptide pretreatment.
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Tesamorelin and liver fat: a trial in people living with HIV
A liver-fat endpoint was examined in a narrowly defined clinical population.
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Early MMPOWER findings: why the statistical analysis matters
A small early study illustrates the difference between promising signals and confirmed outcomes.
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Phosphorylated DSIP in hypoxia: a modified peptide and a specific model
Rats under simulated high-altitude conditions were assessed for sleep architecture, spatial memory and signaling after a phosphorylated DSIP intervention.
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Surface-supported peptide synthesis: stability and purity can trade off
Three surface-functionalization chemistries were compared using model peptide synthesis and surface and mass-spectrometric measurements.
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A DSIP fusion protein: manufacturing and a drug-induced sleep assay
Researchers expressed a fusion containing DSIP, albumin and a transduction domain in yeast, then tested it in a mouse sedative assay.
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Kisspeptin and brain imaging: a mechanistic human study
Brain imaging can investigate a pathway without proving a clinical treatment effect.
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Selank in IMR-32 cells: a null result alone, interactions in combinations
The cell experiment did not find a standalone Selank effect on the measured gene panel.
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DSIP in stressed rat liver: nonuniform antioxidant responses
Acute and chronic restraint-stress experiments measured liver oxidative markers and circulating biochemical endpoints across exposure conditions.
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